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HOME NEW PROJECTS ON-GOING PROJECTS

 

coordinating office:

Professor R-O.Mirimanoff

Professor E.M. Ozsahin

administrator:

Brigitte Pointet

Department of Radiation

Oncology, Centre Hospitalier

Universitaire Vaudois (CHUV)

Rue du Bugnon 46, CH-1011 LAUSANNE, Switzerland 

 

© RCN 2004-2014
webmaster@rarecancer.net

projects_publications

updated 24.04.2014 

1. SEMINOMA+HCG

Mirimanoff RO, Sinzig M, Kruger M, Miralbell R, Thoni A, Ries G, Bosset JF, Bernier J, Bolla M, Nguyen TD.

Int J Radiat Oncol Biol Phys 27: 17-23,1993


(132 patients)

2. UROTHELIAL RENAL PELVIS AND URETER

Ozsahin M, Zouhair A, Villa S, Storme G, Chauvet B, Taussky D, Gouders D, Ries G. Bontemps P, Coucke PA, Mirimanoff RO.

Eur J Cancer 35(5) : 738-43, 1999

(138 patients)

3. TESTICULAR LYMPHOMA
Outcome And Patterns Of Failure In Testicular Lymphoma

 

Patterns of Outcome and Prognostic Factors in Large Cell Lymphoma

Joint Study with the IELSG and the RCN

Zouhair A, Weber D, Belkacemi Y, Ketterer N, Dietrich PY, Villa S, Scandolaro L, Bieri S, Studer G, Delacretaz F, Girardet C, Mirimanoff RO, Ozsahin M

Zucca E, Conconi A, Sarris AH, Seymour JF, Vitolo U, Klasa R, Ozsahin M, Mead GM, Gianni MA, Cortelazzo S, Ferreri AJM, Ambrosetti A, Martelli M, Thiéblemont C, Gomez Moreno H, Pinotti G, Martinelli G, Mozzana R, Grisanti S, Provencio M, Balzarotti M, Lavender F, Oltean G, Callea V, Roy P, Cavalli F, Gospodarowicz MK

Int J Radiat Oncol Biol Phys. 2002 Mar 1;52(3):652-6.

(36 patients)

 

J Clin Oncol 2003 ; 21 :20-27

 

(373 patients)

4. NON SMALL CELL LUNG CANCER
stages i and ii.

Gouders D, Maingon P, Paesmans M, Rodrigus P, Hahn B, Arnaiz MD, Nguyen T, Landmann C, Bosset JF, Danhier S, Van Houtte P.

Rep.Pract.Oncol.Radiother. 8 (1): 7-14. 2003.

Lung Cancer 29 (suppl. 1)
166, 2000

(123 patients)

5. DESMOID TUMOURS

B. Baumert, M. Spahr, A. von Hochstetter, S.Beauvois, C. Landmann, K.Fridrich, S.Villa, M..Kirschner, G.Storme, P.Thum, H.Streuli, N. Lombriser, R.Maurer, G. Ries, E.Bleher, A. Willi, J.Allemann, U. Buehler, H.Blessing, U. Luetolf, J.B. Davis, B.Seifert, M. Infangert

Radiation Oncology 2007, 2:12

(110 patients)

6. ORBITAL LYMPHOMA

Martinet S, Ozsahin M, Belkacemi Y, Landmann C, Poortmans P, Oehlere C, Scandolaro L, Krengli M, Maingon P, Miralbell R, Studer G, Chauvet B, Marnitz S, Zouhair A, Mirimanoff RO.

Int J Radiat Oncol Biol Phys. 2003 Mar 15;55(4):892-8.

(90 patients)

7. UTERINE SARCOMA

Franzetti Pellanda A, Ozsahin M, Deniaud-  Alexandre E, Krengli M, Van Houtte P, Richetty A, Villa S, Kuten A, Jassem J, Bolla M, Hoogenraad W.J, Vaneijkere M. Poortmans P. Collon T, Yavuz A, Chan S, Landman C, Kirkove-Houssiau C. Scandolaro L, Bernier J, Juelke P. Bosmann C. Mirimanoff R.O.

43rd ASTRO, San Francisco, November 4-8, 2001. Int J Radiat Oncol Biol Phys 51: abstr.2213

Full article in preparation

(80 patients)

8. SQUAMOUS CELL CARCINOMA OF THE BREAST

L. Scandolaro

Publication in preparation
(33 patients)

9. ANAL CANAL ADENOCARCINOMA

Belkacemi Y, Berger C, Poortmans P, Zouhair A, Maric J.M, Piel G,Nguyen T.Krengli M,Behrensmeier F, Touboul E.

43rd ASTRO, San Francisco, November 408, 2001. Int J Radiat Oncol Biol Phys 51: abstr. 2063

Int J Radiat Oncol Biol Phys. 2003 Aug 1;56(5):1274-83

(82 patients)

10. BREAST LYMPHOMA

W Jeanneret-Sozzi, A. Taghian,
R. Epelbaum, P. Poortmans,
D. Zwahlen, B. Amsler, B. Castelain,
Y. Belkace?mi, T. Nguyen,
P. Scalliet, P. Maingon,
P. van Houtte,C. Gutie?rrez,
M. Ozsahin, W. Jeanneret Sozzi,

Int J Radiat Oncol Biol Phys 54 (2) suppl. p.300 abstr. 2156, 2002.

BMC Cancer 8(1): 86, 2008.

(84 patients)

11. PLASMACYTOMA
Prognostic Factors In Solitary Plasmacytoma Of The Bone

 

 

 

Outcome And Patterns Of Failure In Solitary Plasmacytoma

Ozsahin M, Tsang RW, Poortmans P, Belkacémi Y, Bolla M, Dinçbas FO, Landmann C, Castelain B, Buijsen J, Curschmann J, Kadish S, Kowalczyk A, Anacak Y, Hammer J, Nguyen TD, Studer G, Cooper R, Sengöz M, Scandolaro L, Zouhair A.

Knobel D, Zouhair A,. Tsang RW, . Poortmans P, . Belkacemi Y,  Bolla M, . Oner FB, Landmann C, . Castelain B, . Buijsen J, . Kowalczyk A, . Anacak Y, . Ozsahin M.

Int J Radiat Oncol Biol Phys. 2006 Jan 1;64(1):210-7

(258 patients)

 

 

BMC Cancer 6(1): 118, 2006

(258 patients)

12. EPIDURAL LYMPHOMA

V Monnard , A. Sun,
R. Epelbaum,P. Poortmans,
T. Verschueren, L. Scandolaro,
S. Villa, S. Balmer Majno,
M. Ozsahin, R-O.
Mirimanoff

ASCO, ECCO, ASTRO and SASRO 2003 [Int J Radiaat Oncol Biol Phys 57 (2 suppl): abst 1046, 2003;

Int. J. Rad. Oncol.Biol. Phys.
2006 Jul 1;65(3):817-23.


(48 patients)

13. ENDOLYMPHATIC SAC TUMORS

U. Abacioglu

Project initiated: Oct 2002, abandoned 2003 due to lack of data

14. ROLE OF RT IN UTERINE PAPILLARY SEROUS CARCINOMA

Goldberg H, Miller RC, Abdah-Bortnyak R, Steiner M, Yildiz F, Meirovitz A, Villa S, Poortmans PM, Azria D, Zidan J, Ozsahin M, Abacioglu U, Gold DG, Amit A, Lavie O, Atahan IL, Kuten A.

Gynecol Oncol. 2008 Feb;108(2):298-305

(138 patients)

15. PHYLLOIDES TUMORS OF THE BREAST

Y. Belkacemi, G.Bousquet, H. Marsiglia, I. Ray-Coquard, N. Magne, Y.Malard, M.Lacroix, Cr. Gutierrez, E. Senkus, D. Christie, K.Drumea, E. Lagneau, S. P. Kadish, L. Scandolaro, D. Azria M.Ozsahin

2004 ASTRO oral presentation
2004 ESTRO poster presentation

Int. J. Rad. Oncol.Biol. Phys.
2008; 70(2):492 - 500

(443  patients)

16. SARCOMAS OF THE BREAST

Bousquet G, Confavreux C, Magne N, de Lara CT, Poortmans P, Senkus E, de Lafontan B, Bolla M, Largillier R, Lagneau E, Kadish S, Lemanski C, Ozsahin M, Belkacemi Y.

 2004 ASTRO oral presentation,
ESTRO 2004 oral presentation
Radiother Oncol. 2007; 85(3):355 - 361

(103  patients)

17. PROSTATE CANCER TREATED BY RADIOTHERAPY IN YOUNG PATIENTS

Tan Dat Nguyen, Philip M.P. Poortmans, Marleen van der Hulst, Gabriela Studer, Eva Pigois, Timothy D. Collen, Yazid Belkacemi, Veronique Beckendorf, Raymond Miralbell, Luciano Scandolaro, Guy Soete, Salvador Villa, Eliahu Gez, Olivier Thomas, Marco Krengli and Nicolas Jovenin

Bull Cancer. 2004Dec;91(12): 959-64

Radiother Oncol.2005 Dec ; 77(3):286-9.

(55 yrs. 39 patients)

18. SMALL CELL CARCINOMA OF THE PELVIS

B. Chauvet

Study abandoned due to limited participation, provision of heterogeneous data leading to difficulty with anatomo-pathological identification of such tumours

19. OLFACTORY NEUROBLASTOMA

M. Ozsahin, O. Olszyk, O. Karakoyun-Celik, B. Pehlivan, D. Azria, M. Roelandts, M. Kaanders, M. Cengi,  M. Krengli, A. Zouhair

Int J Radiat Oncol Biol Phys 2010 78(4): 992-7

(50 patients)

20. MUCOSAL MELANOMA OF UPPER AERO-DIGESTIVE TRACT

Krengli M, Masini L, Kaanders J.H.A.M., Maingon P., Obei S.B., Zouhair A.,Ozyar E, Roelandts M., Amichetti M.8, Bosset M.,Mirimanoff R.O.

Int J Radiat Oncol Biol Phys. 2006; 65 (3):751-9

(74 patients)

21. SMALL CELL CARCINOMA OF THE PROSTATE

M.Stein,Z.Bernstein,U.Abacioglu M.Sengoz,R.S.Miller,A.Mierovitz, A.Zouhair,S.Villa Freixa, P.H.Poortmans,R.Ash,A.Kuten

The Am J Med Sciences
December 2008  336(6):
478-488

(30 patients)

22. DCIS IN PATIENTS YOUNGER THAN 45 YEARS

Omlin A, Amichetti M, Azria D, Cole BF, Fourneret P, Poortmans P, Naehrig D, Miller RC, Krengli M, Gutierrez Miguelez C, Morgan D, Goldberg H, Scandolaro L, Gastelblum P, Ozsahin M, Dohr D, Christie D, Oppitz U, Abacioglu U, Gruber G.

Lancet Oncology 7(8):652-6, 2006


(373 patients)

23. PEDIATRIC NASOPHARINGEAL CARCINOMA

Akman F, Wolden SL, Sarihan S, Miller RC, Ozsahin M, Abacioglu U, Martin M, Caloglu M, Scandolaro L, Szutowicz E, Atahan IL.

Ozyar E, Selek U, Laskar S, Uzel O, Anacak Y, Ben-Arush M, Polychronopoulos S, Akmann F, Wolden SL, Sharikan S, Miller RC, Ozsahin M, Abacioglu U, Martin M, Caloglu M, Szutowicz E, Atahan IL

Proceedings of the 47th Annual ASTRO Meeting, Denver, 2005. Int J Radiat Oncol Biol Phys63(2) Suppl: S23-24, 2005

 

Radiotherapy&Oncology
2006 Oct;81 (1):39-46
.

(165 patients)

24. MELANOMA OF THE RECTUM

D.Azria

Initiated November 2004

(90 patients)

Data will be added to project 73 (Hallenmeier and Azria)

 

25. CEREBELLAR GLIOBLASTOMA MULTIFORME

 

Weber DC, Miller RC, Villa S, Hanssens P, Baumert BG, Castadot P, Varlet P, Abacioglu U, Igdem S, Szutowicz E, Nishioka H, Hofer S, Rutz HP, Ozsahin M, Taghian A, Mirimanoff RO.

 

Int J Radiat Oncol Biol Phys. 2006 Sep1, 66(1), 179-186

(45 Patients)

26.NASOPHARYNGEAL ANGIOFIBROMA

E. Ozyar

Abandoned 2011 due to lack of data

27. ATYPICAL AND ANAPLASTIC (MALIGNANT) MENINGIOMA (WHO GRADE II AND III)

Pasquier D, Bijmolt S, Veninga T, Rezvoy N, Villa S, Krengli M, Weber DC, Baumert BG, Canyilmaz E, Yalman D, Szutowicz E, Tzuk-Shina T, Mirimanoff RO;

Int J Radiat Oncol Biol Phys. 2008 Aug 1;71(5):1388-93.

(119 patients)

28. MALT LYMPHOMA OF THE SALIVARY GLANDS

Y. Anacak, R.C. Miller, N. Constantinou, A.M. Mamusa, R. Epelbaum, Y. Li, A.L. Calduch, A. Kowalczyk, D.C. Weber, S.P. Kadish, N. Bese, P. Poortmans, S. Kamer, M. Ozsahin.

Int J Radiat Oncol Biol Phys 2010 Nov 12.

Int J Radiat Oncol Biol Phys 2012;82:315-20

59 patients

29. CURATIVE EXTERNAL BEAM RADIOTHERAPY IN PATIENTS OVER 80 YEARS OF AGE WITH LOCALIZED PROSTATE CANCERS

T.D. Nguyen, D Azria, D Brochon, P Poortmans, RC Miller, L Scandolaro, W Majewski, M Krengli, U Abacioglu, L Moretti, S Villa, F Akyol, N Jovenin

Cancer Radiother 2009; 13(6-7), 622-7

Crit Rev Oncol Hematol 2010;74:66-71

(65 patients)

30. RADIOTHERAPY IN ERDHEIM - CHESTER DISEASE (NON LANGERHANS CELL HISTIOCYTOSIS)

Miller RC, Villa S, Kamer S, Pasquier D, Poortmans P, Micke O, Call TG.

Radiother Oncol 2006; 80 (3): 323-326

(9 patients)

31. PRIMARY INTRA-OCULAR LYMPHOMA

K. Mak, R. Miller, S. Krishnan, N. Laperriere, O. Micke, I. Rutten, S. Kadish, M. Ozsahin and R-O. Mirimanoff

ASTRO abstract

Int J Radiat Oncol Biol, 2007; 69(3)
S534 - S535

(20 patients)

32. GIANT CELL TUMORS OF THE BONE

S. Bhatia, L. Miszczyk, M. Roelandts, T. Nguyen, T. Boterberg, P. Poortmans, Vallow L, Dincbas FO, Lassen-Ramshad Y, Botras M Miller RC

Rare Tumors 2011; 3 (4) e:48

(39 patients)

33. CASE -CONTROL STUDY IN RADIATION - INDUCED ESOPHAGEAL CANCER*

G. Crehange

Publication in preparation

 34. SPINAL MYXOPAPILLARY EPENDYMOMA*

Pica A, Miller RC, Villa S,Kadish S, Anaçak Y, Abusaris H, Ozyigit G, Baumert BG, Zaucha R, Haller G, Weber DC

Int J Radiat Oncol Biol Phys 74(4): 1114-20, 2009

(85 patients)

 35. PRIMARY PINEAL PARENCHIMAL TUMORS

 S.Villa, RC Miller, M Krengli, H Abusaris, BG Baumert, S Servaji-Vernat, S Igdem, A Lucas, S Boluda, RO Mirimanoff

Clin Transl Oncol 2012; 14: 827-34

Abstract ASTRO 2008
Oral presentation at EANO, 2008

(35 patients)

36. LOW GRADE PRIMARY MENINGEAL LYMPHOMA

D.Weber

Study abandoned due to lack of patients

37. ADULT LANGERHANS CELL HISTIOCYTOSIS OF THE BONE

Atalar B, Miller RC, Pincbas FO, Geismar JH, Micke O, Akyurek S,  Ozyar E.

Acta Orthop Belg 2010; 76:663-8

(30 patients)

38. SMALL CELL ESOPHAGEAL CARCINOMA

P. Vos B, Rozema T, Miller RC, Hendlisz A, Van Laethem JL, Khanfir K, Weber DC, El Nakadi I, Van Houtte P

Dis Esophagus 2011 ; 24 :258-64

(24 patients)

39. THYROID LYMPHOMA

Onal C, Li YX, Miller RC, Poortmans P, Constantinou N, Weber DC, Atasoy BBM, Igdem S, Ozsahin M, Ozyar E

Ann Oncol. 2011 ;22(1):156-64.

(87 patients)

40. GLOMUS TUMORS OR PARAGANGLIOMAS*

Y. Lassen-Ramshad

Initiated June 2007

Accrual extended

41. DUCT CARCINOMA OF THE PROSTATE*

Igdem S, Spiegel DY, Efstathiou J, Miller RC, Poortmans P, Koca S, Kiliç-Unsal D ; Okkan S, Zietman A

ASTRO 2009: Int J Radiat Oncol Biol Phys 75(3) suppl. p.S300-301, 2009.

Onkologie 2010;33:169-173

(31 patients)

42. PRIMARY SPINAL HODGKIN'S LYMPHOMA

D. Weber

Initiated July 2007

Study abandoned due to lack of patients

43. ADENOID CYSTIC CARCINOMA OF THE BREAST

Khanfir K, Kallel A, Villette S, Belkacémi Y, Vautravers C, Nguyen TD, Miller RC, Li YX, Taghian A, Boersma L, Poortmans P, Goldberg A, Vees HJ, Senkus E, Igdem S, Ozsahin M, Jeanneret-Sozzi W.

Abstract SASRO 2009

 

Int J Radiat Oncol Biol Phys 2012; 82:2118-24

 

(61 patients)

44. UTERINE SARCOMAS*

(exluding leiomyosarcoma)

H. Vees

Initiated November 2007
150 patients under analysis

Abstract submitted to ECCO 2009

45. ANAL INTRAEPITHELIAL NEOPLASIA (AIN)

G. Crehange

Study abandoned 2011 due to lack of patients

46. ONCOCYTIC TUMORS OF THE CHOROIDAL PLEXUS

R. C. Miller

Initiated June 2008
Study abandoned due to lack of patients

47. MUCOSAL KAPOSI SARCOMA (MKS)

Thariat J, Kirova Y, Sio T, Choussy O, Vees HJ, Schick U, Poissonnet G, Saada E, Thyss A, Miller RC

Rare Tumors 2012; 4(4), e49

(15 patients)

48.PRIMARY HEPATIC LYMPHOMA

G.Ugurluer,

E-M.Ozsahin,

U. Schick

Initiated March 2009

Accrual survey

49. OSTEOSARCOMA OF THE MANDIBLE

 

(Joint study with the French Sarcoma and Bone Tumor Group) and the GETTEC:(Groupe d’Etude des Tumeurs de la Tete et du Cou).and RCN

 

*

Thariat J, Schouman T, Brouchet A, SariniJ, Miller RC, Reichler H, Ray.Coquard I, Italiano A, Verite C, Sohawon S, Bompas E, Dassonville O, Salas S, Aldabbagh K, Maingon P, de la Motte Rouge T, Kurtz JE, Usseglio J, Kerbrat P, Raoul G, Lotz JP, Bar-Sela G, Brugnières P, Chaigneau L, Saada E, Odin G, Marcy PY, Thyss A, Julieron, M.

 

Annals Oncol 2013; 24: 824-31

 

(111 patients)

50. PRIMARY NON-HODGKIN'S LYMPHOMA OF THE PROSTATE

D. Weber

Initated December 2009

Study abandoned due to lack of patients

51. PRIMARY BONE LYMPHOMA

Cai L, Stauder MC, Zhang YJ, Poortmans P, Li YX, Constantinou N, Thariat J, Kadish SP, Nguyen TD, Kirovy YM, Ghadjar P, Weber DC, Bertran VT, Ozsahin M, Mirimanoff RO

 Int J Radiat Oncol Biol Phys  2012; 83:284-91

52. PROGNOSTIC FACTORS AND MANAGEMENT OF RARE CANCERS

Y. Belkacemi, A. Zouhair, M. Ozsahin, D. Azria, R.O. Mirimanoff

Cancer Radiother 2006; 10(6-7): 323-9

(review in french)

53. ADULT MEDULLOBLASTOMA

Banu Atalar

Initated September 2011

54. MULTIPLE BONE LYMPHOMA

C. Ling, R.O. Mirimanoff

8 cases, under analysis  March 2014

55. MERKEL CELL CARCINOMA

Ghadjar P, Kaanders JH, Poortmans P, Zaucha R, Krengli M, Lagrange JL, Ozsoy O, Nguyen TD ; Miralbell R, Baize A, Boujelbene N, Collen T, Scandolaro L, Untereiner M, Goldberg H, Pesce GA, Anacak Y, Friedrich EE, Aebersold DM, Baer KT

Int J Radiat Oncol Biol Phys 2011 ; 15 : 583-91

(180 patients)

56 ENDOMETRIAL STROMAL TUMORS

Schick U, Bolukhasi Y, Thariat J, Igdem S, Caglar H, Ozsahin M, Lössi K, Schleicher U, Zwahlen D, Villette S, Vees HJ

Int J Radiat Oncol Biol Phys 2012; 82:757-63

 

(59 patients)

57. THE RARE CANCER NETWORK ACHIEVEMENTS 1993-2012

Patel A, Ozsahin M, Mirimanoff RO, Bhatia S, Chung K, Miller RC

Rare Tumors 2012 ;43-e35

58.EXTRASKELETAL OSTEOSARCOMA

Sio TT, Vu TT, Sohawon S, van Houtte P, Thariat J, Novotny PJ, Miller RC, Bar-Sela G.

Am J Clin Oncol 2014 ;e pub

(138 patients)

59.ADENOSQUAMOUS TUMORS OF THE HEAD AND NECK

Schick U, Pusztaszeri M, Betz M, Ghadjar P, Demiroz C, Kaanders JH, Ozsahin M,

Oral Surg Oral Med Oral Pathol Oral Radiol 2013; 116:313-20.

(20 patients)

60. SQUAMOUS CELL CARCINOMA OF THE ECTUM

K Khanfir

Interest Evaluation 2010

Under analysis 2014

61. SALIVARY GLAND CANCER

J Thariat and XS Sun

Interest Evaluation 2010

62. PRIMARY HEPATIC LYMPHOMA

G Ugurluer and M Ozsahin

Interest Evaluation 2009

63. ROSAI-DORFMAN DISEASE

R Miller and K Chang

Interest Evaluation 2008

64. NON ANAPLASTIC THYROID CANCER

J. Thariat and XS Sun

Interest Evaluation 2012

65. ANAPLASTIC THYROID CANCER

J Thariat and XS Sun

Interest Evaluation 2012

66.DUCTAL IN SITU MALE BREAST.

O. Micke

Interest Evaluation 2011

67. SMALL CELL BLADDER CANCER

D Pasquier

Interest Evaluation 2010

Abstract submitted, Article in preparation 2014

68. ADENOID CYSTIC CANCER OF THE LACRYMAL GLAND

C Ares

Data Collection 2006

69.CARDIAC SARCOMA

J Thariat, and K Clement Kolmou

New Project 2014

70. SOLITARY FIBROUS TUMORS

J. Rooney

New Project 2014

71 . MIDLINE NUT CARCINOMA

R Funk

New Project 2014

72. TUMORS OF THE AMPULLA OF VATER

S. Krishnan

New Project 2014

73. ANORECTAL MELANOMA OF THE RECTUM

C. Hallenmeier and D. Azria

New Project 2014

Data collection

74. ADENOID CYSTIC CARCINOMA OF THE TRACHEA

P. van Houtte

New Project 2014

75 HEMANGIOPERICYTOMA

M Krengli

New Project 2014